Synthesis Of Aspirin And Oil Biology Essay

Synthesis Of Aspirin And Oil Biology Essay Esterification is the reaction between carboxylic acids and alcohols to produce esters. Aspirin or acetylsalicylic acid was formed by reacting salicylic acid and acetic anhydride while Methylsalicylate was formed from salicylic acid and methanol, both in the presence of H2SO4 responsible for the removal of -OH to form an ester and donates H+ to protonate the salicylic acid. The reaction mixture in the synthesis of aspirin should be heated in temperature between 70-90Â °C for the formation of acetylsalicylic acid crystals that was further collected using vacuum filtration with cold water to wash out the impurities and further produced a 57% yield product. The synthesized methylsalicylate resulted to a minty odor that is used mainly as ointment or cream for treating muscle pains and sprains. Test using FeCl3 to verify the purity of the synthesized aspirin resulted to a violet-colored solution in acetylsalicylic acid making it an impure product because of the presence phenol group that must not be present in the structure. However, positive result in methylsalicylate turned the solution from clear to dark-green and further to a purple solution due to the presence of phenol group. The results of the experiment are therefore accurate and useful in knowing the importance and uses of organic products and knowing the process of esterification involving carboxylic acids and alcohols. __________________________________________________________________________ INTRODUCTION Aspirin or acetylsalicylic acid from a family of chemicals known as salicylates is known to be an anti-inflammatory drug and used as a pain reliever (1). On the other hand, oil of wintergreen or methylsalicylate is an external analgesic used to treat muscle aches, sprain, and strains having anti-inflammatory and pain-relieving effects as well (4). Both the aspirin and methylsalicylate can be produced from salicylic acid, a natural occurring chemical in plants, consisting of two functional groups carboxylic acid and phenol. The synthesis of acetylsalicylic acid and methylsalicylate from salicylic acid results in the formation of ester in the process called esterification where an acid reacts with an alcohol (2). The purity of the synthesized aspirin will be tested by using FeCl3 test where a purple color will determine the presence of the phenol group where the -OH group in the benzene ring will form a complex with Fe+3 (3). MATERIALS AND METHODS For the making of aspirin, a water bath with temperature ranging from 70-90Â °C was prepared while weighing 0.150 g of salicylic acid and dropped 85% H2SO4. Then, 0.3 ml of acetic anhydride was added to the reaction mixture and heated with the prepared water bath until it dissolved. Then, it was recrystallized in an ice bath after adding 0.2 ml deionized water. The formed aspirin was collected using vacuum filtration, washed with cold water, allowed to dry overnight and weighed again to calculate for the percentage yield. For the making of the Methylsalicylate, 0.25 g of salicylic acid was used and added 2.0 ml methanol until it dissolved. Then, 10 drops of H2SO4 was added and heated in the water bath for 15 minutes followed by allowing it to cool down in running water. The odor of the product formed was then determined. For the FeCl3, the synthesized aspirin and methylsalicylate were added 5 ml of distilled water and a drop of 1% FeCl3 to the test tubes for observations. RESULTS AND DISCUSSIONS Esterification involving salicylic acid and methanol will produce methylsalicylate that has pain-relieving and anti-inflammatory effects while salicylic acid and acetic anhydride in excess will form acetylsalicylic acid in the presence of H2SO4. The results and observations gathered in the experiment involving the FeCl3 test are summarized in Table 1. Table 1. Data and Results for the Yield of Aspirin and FeCl3 Test A. Yield of Aspirin Mass of Salicylic Acid 0.150 g Mass of acetyl salicylic acid 0.114 g % Yield 57 % B. FeCl3 Test Sample Observation Acetylsalicylic acid Violet-colored Methylsalicylate Liquid; From clear to dark-green solution; Addition of cold water turned into dark purple The aspirin or the acetyl salicylic acid was formed by reacting 0.150 g of salicylic acid with acetic anhydride with the presence of acid catalyst which is H2SO4 to speed up the reaction as well as being responsible in removing the -OH to form an ester. The acid catalyst donates H+ and protonates the salicylic acid as shown in Figure 1. Figure 1. Reaction of salicylic acid with acetic anhydride Acetic anhydride was used for the reaction will be much faster and will produce a higher percentage yield (5). The reaction mixture was heated in the water bath with temperature between 70-90Â °C to aid in the formation of acetylsalicylic acid crystals and thus making the acetic acid as a byproduct. The salicylic acid dissolved while in the water bath due to the increased heat and increased solubility that made the solution colorless and allowed the salicylic acid white crystals to dissolve. The addition of water after removing the reaction mixture in the water bath aid in destroying the excess acetic anhydride that is unreactive. Then, recrystallization was performed in an ice bath since cooling of the mixture forms white crystals by decreasing its solubility. The aspirin was collected using vacuum filtration while washing it with cold water to separate the solid crystals as well as the removal of impurities in the crystals. After drying, 0.114 g of acetylsalicylic acid was obtaine d with a yield of 57% with calculations shown in Figure 2. Thoretical yield = 0.150 g x x x = 0.20 g Actual yield (Mass of acetyl salicylic acid) = 0.114 g 57%% Yield = x 100 = x 100 = Figure 2. Calculations for the % Yield of the Synthesized Aspirin The methylsalicylate or oil of wintergreen was also formed from salicylic acid where it reacted with methanol in the presence of H2SO4 again for the removal the -OH to form an ester in the reaction called esterification as shown in Figure 3. The sulfuric acid as a catalyst protonates the ester group while the methanol attacks the carbonyl group. As the carbonyl group was deprotonated, methylsalicylate formed. Figure 3. Reaction of salicylic acid with Methanol The product formed a minty odor that is used in food, perfumery, toothpaste, and candies or used as pain-reliever. The purity of the synthesized aspirin and methylsalicylate were tested using FeCl3 to test for the presence of phenol. The acetylsalicylic acid resulted to a violet-colored mixture indicating that the product formed has impurities since the synthesized aspirin or acetylsalicylic acid does not have an OH group, however, it turned violet or dark purple due to the presence of salicylic acid that didnt react purely in the process. On the other hand, methylsalicylate in FeCl3 gave a positive result where it turned dark-green and further into dark-purple due to the presence of phenol thus making the methylsalicylate as a pure product. Over all, the results of the experiment are accurate and useful in appreciating products that occur naturally as well as knowing how to synthesize aspirin and oil of wintergreen from salicylic acid.

Home Decision

Woven Shivers It is really nice to have an investment of your own, especially when the money comes from your own pocket (2012, First Time Home Buyers). Like for example, one of the best investments that a person could have in their life is to have his or her own home, a home that he or she could call their own. When It comes to purchasing a car, new home or even clothing you must weigh the benefits and cost properly so that you do not lead yourself down a path of financial ruins.While the idea of purchasing new home Is very excellent, It can also sometimes be overwhelming. A significant amount of time for consideration and evaluations Is necessary when making a major purchase such as buying a new home. Purchasing a home can have severe financial repercussions, thus making the decision to purchase a new home a daunting and challenging choice, so when making a large financial decision, the basic principles of economics along with one's relative needs you must closely assess.Many of the decisions we make as consumers directly relate to the current state of the economy. While the search for a new home continues, a couple of key principles should be used and will prove to be rather helpful to the new homemaker. Comparing marginal costs with marginal benefits while weighing out the disadvantages and advantages of the purchase Is included In this process (NAB, 2011). As homeowners have testified, a couple of key principles will contribute to this life-changing decision. Trade-offs† Is one of the principles you will face before and after your purchase. That meaner that there Is a cost for everything. When a major purchase decision Is made nonusers definitely have to give up another thing that they equally like such as a new car, vacation, other major purchases, or savings and investment. Trade-offs exist for almost every decision contemplated, but in the real estate market, trade-offs can be serious when money is the concern.Neither buyer nor seller wants to lose money in one of the biggest transactions they will ever complete. You can make better decisions when you realize that life has tradeoffs. The cost of what one decides to buy is equivalent to the cost of what one gives up for it. Choosing entails riding off a target against another and is a fundamental Issue of the decision- making process. In order to purchase a beautiful home, one will have to sacrifice â€Å"opportunity cost†; for Instance, I have to cut-down on Individual costs like entertainment, clothing and food.When you have to choose one thing over another then you have to make do without the benefits of that which you do not have. You have to compare the cost and benefits of what you have to make the best choice. For graduate more opportunities begin for a better paying Job. However, in this market he opportunity cost is typically minimal because the buyer can simply find another home that meets his or her needs. Cost is not a matter of dollars and cents; it also re presents what we must give up to get something else.In reality, we do not always make decisions that are all or nothing. Some choices are made based on â€Å"marginal changes†. When we think of purchasing a home one must compare the marginal cost of purchasing a home. Amortization is a marginal cost, will the payments be an addition to what you are already paying if you are renting. The difference in the mount is marginal cost. You must also consider the mortgage insurance cost, as a result, of purchasing a home. Will the house be bigger, adding more room for your growing family?Will utilities be higher? Other marginal cost to be considered would be; the cost of moving, your travel time, the expense of gas and mileage on your car, which is associated with your travel time, if your new home is further away from your place of work compared to your current apartment. The maintenance cost of a new home must be considered because the owner of a home is solely responsible of aging sure their home is maintained and secure. Consider all of the benefits and costs that a home presents. What might a year of security monitoring cost?Assign a value to benefits or costs that do not have an explicit price tag. The benefits of living closer to the Job could be calculated as more pay for work from extra hours that would otherwise be spent commuting from a home further away. Your optimal goal is to find a home in which the total benefit, marginal and otherwise, exceeds the total cost. While one considers the marginal cost, you must also consider the benefits. Consider the marginal benefits of owning your own home. The tax shield with renting an apartment, and we must compare the marginal benefits (the Joy) of owing your own home.The tax break and financial security of owning a home are essential in appreciating the purchase off new home. In a decision to purchase a home you must carefully analyze the cost and benefits in order to make the most rational decision for your family. Investments can sometimes be confusing, especially on real estate. One must always be careful when investing in the purchase off new home cause this is not Just money it is your hard-earned dollars you will be investing and unlike a pair of shoes you can't return it if you don't like it.The economy plays a major role in the decision to purchase a new home. If the economy has recovered fully or still at a low point, one thing is for sure, your finances must be secure no matter the rates. The economy is made up of different factors such as trading, exporting and importing, unemployment, house market and inflation. The economy plays such an important role because home prices are usually very high and will quire a substantial down payment, (most lenders require around 3. 5% of the value of the home), which may sometimes deplete your savings.The demand for houses is considered highly price elastic. Economic theories state that the larger the proportion of income a certain purchas e requires the more price elastic the demand will be. Your lender will explain that your house payment should not exceed more than one third of your monthly income. You, as the buyer, should have an understanding, as it will require the spending of a large proportion of your income, so this will inconsiderably lower your purchasing power when you decide to make the purchase of program if unemployment falls to under 7 percent. Unemployment is projected to reach 6. percent in 2014, according to the Feeds projections. Currently, unemployment stands at 7. 6 percent (Brenan, 2013). Brenan said that if the economy continues to show improvement the Fed will â€Å"ease the pressure on the accelerator†. The Fed has kept interest rates low to stimulate the economy and the low rates have helped boost housing affordability. The federal government will adjust accordingly if the economy veers from projections. The housing sector is looking a little better so the state and local governments are in a position where they do not have to lay off many workers.That meaner that the economy is improving. Domestic economy is the made up of several components such as government spending, trade, level of consumption and investments. The strength of the economy is affected by changes in these components. Domestic economy and international trade play an important role in affecting the economy. If government spending increases, it will help the GAP (growth domestic product). Because of this, we have economic growth in which will increase Jobs and wages but if the government spending decreases, the effect is contraction.This is somewhat of a ripple effect because it reduces the GAP, which thus reduces the level of income and number of jobs in the economy. International trade affects the countries balance and trade. We make choices daily based on the benefits. We have the freedom to want whatever but the resources to obtain that is limited. In our day-to-day life, we use several prin ciples to make decisions. We often-times make choices by realizing what SST be given up to gain something else or something better.Studies show that once consumers buy a home, get a mortgage and have a positive experience owning, they wanted to continue to own. In a study concerns about affordability both for the home purchase itself and upkeep was a major factor that discouraged renters from taking the plunge (Tara Bernard, 2012). A personal example off decision in which I compared marginal benefits and marginal costs associated with the decision was the time I decided that I was not happy in my Job and that the only way for me to et a better Job would be to go back to college to earn my degree.The reason I wanted to earn a college degree was for better Job advancement and better Job opportunities. Financially, the rate of return made my decision easy. In addition, college graduates enjoy better health, save greater percentage of their income; improve quality of life for them and t heir family (Sweatier, DCE. 2011). The marginal costs of my decision was the time and effort it took to complete course work, time away from family, the commuting and the stress of starting back to school at my GE after years of not attending.The incentives that would have led me to make a different decision might have been a Job in my field of expertise, more and better Job opportunities and more opportunities that did not require a college degree. After looking over all of the pro and cons of buying a house in the current market, I have concluded that it is the perfect time to purchase a home for my family and l. The government has been influenced by the recession to increase incentives for recurring as well as new buyers, in addition to low interest rates, and the large amount of repertoires to choose from.If the market were balanced, unemployment was at an all-time low and inflation was not so high, I believe I would not be able to afford the dropped to comparable prices, then I feel I would not be able to afford the over- priced properties. For new home buyers, the tax credit is a great incentive; without it, I wouldn't even consider buying a new home. Therefore, I am only able to buy a new home in this economy and be able to take full advantage of the incentives which comes along with the market, while making the best use of my marginal benefits and re worth all of the subsidiary costs.

Rhetorical Reading Strategies and the Construction

Rhetorical Reading Strategies and the Construction of Meaning Summary Although the collective knowledge in the field of Pedagogy on how readers, â€Å"actually carry out this interpretive process with college-level expository text is rather limited† (Haas and Flower 167). The study in discussion would like to help the understanding of this constructive, rhetorical view of reading.Throughout the article, Haas and Flower emphasize how students â€Å"are good readers in the traditional sense†¦ yet, they paraphrase rather than analyze, summarize rather than criticize texts† (170). This brings up two key points that Haas and Flower discuss in a relation to rhetorical reading strategies, in student reader-writers. According to the research Haas and Flower conducted, only about one percent of students use the rhetorical reading strategy, which means that most students don’t criticize and analyze text that they read.Most students mainly use the Content and Feature/F unctional reading strategy, rather than deconstructing the text, they just say the basic things, and summarize which brings up the question, how does the constructive process play itself out in the actual thinking process of reading? Haas and Flower purpose that readers â€Å"construct meaning by building multifaceted, interwoven, representation of knowledge† (168).The main focus Haas and Flower have throughout the article is the fact that students are staying at the â€Å"mediocre† level while reading, instead of breaking down the text and actually analyzing what the author(s) were trying to say. Haas and Flower want students to get use to using the rhetorical strategy, since it will help students better understand the text they read especially as they continue on with higher education Works Cited Haas, Christina and Flower, Linda. â€Å"College Composition and Communication† Reading Strategies and the Construction of Meaning. 1988

Research Study- Factors Affecting Team Conflict and...

Conflict is a basic aspect of teamwork (Levi, 2001), since the number of decisions that a team needs to make often evokes feelings of discomfort and stress. Conflict very often arises from a clash of different working style, ideas, interests, needs, and wants. With respect to these clashes, the literature describes two levels of conflict: relationship and task. Relationship related conflicts are based on relationship with team members, when team members have interpersonal in compatibility (Stewart, Sims, Manz, 1999) relationship conflicts are more difficult to address and identify because they are less explicit. There are wide range of factors from which relationship conflicts can derive. These factors are: lack of communication,†¦show more content†¦maintain team structure and climate, apply problem solving strategies, communicate with the team members, execute plans and manage workload, and improve team skills. The objective was to improve team opinions, behaviors and attitudes and team performance and evaluate the effectiveness of the team performance (Risser, Rice Simon, 1999). When trust is not there then no other components are sufficient to sustain a team. All other components are subordinate to trust. The research shows that each of the subordinate components can impact trust but trust is an element in its own right; separate from other element while at the same time, composed of them (Thaker Yost, 2002). There is no relationship between trust and performance because trust in inversely associated with conflicts (Shrum, Chompalov Genuth, 2001). When there are conflicts in the team then its difficult to maintain and develop the team performance and in such situations team will shatter. When task conflicts become prominent then its become difficult to take decisions (De Dreu Weingart, 2003). The research has showed the presence of both types in any group setting; but hes clear to explain that cognitive conflict is constructive, while affective conflict is destructive (Brockmann, 1996). To improve the quality of product or service or overall performance, many organizations have focuses on team building. However they ignore the basic elements of efficientShow MoreRelatedImpact of Cultural Differences, Internal and Environmental Factors at Airbus1619 Words   |  7 PagesImpact of cultural differences, internal and environmental factors at Airbus Introduction Employees are affected by a number of internal and external forces that when combined produce given behaviours and attitudes. In this paper, I will consider the key factors affecting individual and groups’ behaviour and their corresponding relationship to the personal and organisational performance. The scenario, Airbus’ manufacturing plant in Toulouse, is dominated by tensions amongst groups of workersRead MoreLeadership And Its Effect On Employee s Productivity1568 Words   |  7 Pages Leadership is a crucial concept in the organizational sciences and has prompted many researchers to study its effects and benefits on management as well as its effects on employee’s productivity. In the structure of an organization or institution, the position of leadership is fundamental for its proper function and operation. Leadership is about having the ability to influence others. Having influence means that there is a greater need on the part of leadership positions to exercise their influenceRead MoreWorkplace Attitudes and Job Behaviors Essay examples2317 Words   |  10 PagesThis study aims to increase understanding of factors that influence employees’ reactions in the workplace. The relationship between conflict among employees, the perception of organizational politics, conflict or ambiguity of workplace roles and several other work outcomes was explored by studying 11 research articles to investigate individual and organizational effects of workplace attitudes and behaviors. Employees need to work together toward common goals in order for an organization to functionRead Moreproject manajment1121 Words   |  5 PagesIntegration of projects with the strategic plan Integration within the process of managing actual projects Research Highlights: Chaos: Software Projects Summary Text overview Review questions exercises Case: South American Adventures Unlimited CHAPTER 2 Integration of Organization Strategy with Projects Strategic management process: an overview Research highlights: Muddling Absence of a priority system linked to strategy creates problems SnapshotRead MoreMindfulness And Its Impact On The Workplace Essay1649 Words   |  7 Pagesreflected of how individual response and having awareness about present events (Quaglia, Brown, Lindsay, Creswell, Goodman cited in Good., et al 2016). Moreover, the research on management also revealed from integrative framework that mindfulness has positive effect to individual hence will affecting positive outcomes to organization. Conventional stigma of how people see process of managing can only be developed by experiences diminished slowly because mindfulness could be learned with training.Read MoreOrganizational Behavior : The Department Of Human Resource And Management1524 Words   |  7 Pagesideals may differ from the organization mission. Therefore an organization advance and productivity need strategies that accommodate people diversity characteristics. The department of human resource and management makes plan to deal with diversity. Diversity issues involves individual charact eristics, an individual primary characteristic refers to individuals biological traits such as gender, race, sexual orientations and others. Secondary characteristics are factors that may be changed such asRead MoreTeamwork and Accountability1472 Words   |  6 Pagesobjectives of the organization and developing business models that monitor and ensure compliance with ethical standards, norms and laws. Teamwork Teamwork has become increasingly more popular in organizations. In order for teams to be successful it is important that individuals have the tools necessary to align their tasks with a shared goal. Teams must be able to provide the necessary feedback and support to continue to improve the process and outcomes that define a team’s goal. Teams, just like peopleRead MoreOrganizational Analysis of Hospital Z Essay1008 Words   |  5 PagesSuccessful medical organizations have as their guiding principles a professionally stated purpose which encompasses and details their mission statement, vision statement, values statement, and broad strategic goals. The organizational structure is established on these statements, and the function of each department and the duties of each employee are based upon fulfilling the purpose of these statements. Additionally, these statements must encompass the various aspects of the organization and its stakeholdersRead MoreEmployee Participation in Decision Making1447 Words   |  6 Pagesemployees in decision making process of organization. During the last two decades the revolutionary steps that have been initiated to facilitate the high performance working mainly focused on increasing the ways of joint consultation, which attracts both employers (who demand better business results) and employees (who demand recognition and protection of employee rights) (CIPD, 2009). Employee voice is a very important factor in the success of an organization. Dundon et al. (2004) argues that successfulRead MoreThe Impact Of Diverse Top Management Teams On Corporate Strategies And Performance6426 Words   |  26 PagesTHE IMPACT OF DIVERSE TOP MANAGEMENT TEAMS ON CORPORATE STRATEGIES AND PERFORMANCE Dissertation Proposal Submitted to Northcentral University Graduate Faculty of the School of XXXXXXXX in Partial Fulfillment of the Requirements for the Degree of DOCTOR OF XXXXXXXXXX by NAME Prescott Valley, Arizona Month Year Abstract The business landscape has been dramatically changed and overhauled by the globalization process in today’s world. Adoption of diversity by many firms is in the aim